Wall Street tumbles at open as Trump tariffs loom

US stock indexes opened sharply lower on Wednesday as investors awaited details of US President Donald Trump's tariffs to assess their impact on the global economy, corporate earnings and inflation.

The Dow Jones Industrial Average fell 342.35 points, or 0.82 percent, to 41,647.61, the S&P 500  fell 57.65 points, or 1 percent, to 5,577.02 and the Nasdaq Composite fell 241.23 points, or 1.38 percent, to 17,208.66.

REUTERS